In clinical treatment, there is generally no dependence on compound licorice tablets when taken for a short period of time. However, if you take compound licorice tablets for a long time, for example, up to half a year or even more, you may develop drug dependence. The main active substance of the opioid is morphine, the content of which is so small that if taken for a short period of time, it can be cleared up quickly through human metabolism and will not cause dependence on the human body. However, if taken for a long time, the body will become dependent because the concentration of opioids in the blood will remain constant, causing drug addiction, so compound licorice tablets will have dependence when taken for a long time and should not be taken for a long time.