The severity of membranous nephropathy can generally be analyzed by 24-hour urine protein quantification, renal function, pathological type, etc., and cannot be generalized. 1. 24-hour urine protein quantification >3.5g is a large amount of proteinuria, persistent proteinuria tends to be more serious. 2. If renal function is reduced at the time of diagnosis, patients with progressive deterioration of renal function during the course of the disease are in more serious condition. 3. Renal biopsy pathological staging, renal tubular atrophy, renal interstitial fibrosis and other pathological changes are more serious. 4. In addition, the prognosis of children is generally better, and the prognosis of patients over 50 years old is worse; women usually have a better prognosis than men; those who have serious complications have a worse prognosis and their condition is relatively serious. It is recommended that patients with membranous nephropathy go to the hospital as soon as possible and actively cooperate with doctors to prevent the development of the disease.