Osteoarthritis of the knee, also known as degenerative joint disease and hypertrophic osteoarthritis, is a chronic aseptic inflammatory disease. It is more common in middle-aged and elderly patients, more women than men, with a prevalence of up to 50% over the age of 60 and up to 80% at the age of 75, and a disability rate of up to 53%, which may result in a shorter life expectancy. Like wrinkles and gray hair, a weak knee joint is the first sign that a person is aging. Once the joint ages, the knee has to begin a long period of chronic pain. Age-related knee osteoarthritis is a common chronic disease with intra-articular pain and extra-articular pain, with knee and osteoarthritis being the most common. Information shows that there are more than 100 million people with arthritis in China, and the number is increasing. Patients may have no symptoms or minimal pain in the early stage, and then gradually develop mild to moderate pain and joint stiffness, mostly during activities and relieved after rest, such as pain when squatting, turning, standing up after sitting for a long time, or going up and down stairs. In severe cases, tearing or pins-and-needles pain may occur, and even joint interlocking may occur. Knee pain should not be tolerated, but treated actively and promptly. 1.No need for surgery: Trioxane treatment is convenient and quick, with fast results, and no surgery is needed. 2.Inhibit inflammation: After trioxane is injected into the joint cavity, it comes into contact with the synovial membrane, reduces inflammation and eliminates inflammation, inhibits inflammation and exudation of the synovial membrane, and eliminates joint effusion. 3.Repair tissue: Trioxin can induce the production of antioxidant enzymes. Increase the synthesis of interstitial cells and articular cartilage. Stimulate the proliferation of cartilage and fibrogenic cells to play a certain role in repair. 4. Pain relief: After injection, it acts directly on the nerve endings and inhibits the release of intermediate neurogen and enkephalin, so as to achieve the effect of analgesia. Treatment can improve the function of the knee joint, but if patients do not pay attention to self-protection, the result is more and more pain in the joint, the more money spent.