For people who usually have regular menstrual cycles and have their periods in about 30 days, early pregnancy reactions can usually appear around 42 days after menopause, counting from the first day of the last menstrual bleeding. Most of them are nausea and vomiting, especially in the morning after waking up, weakness, easy to get tired, like to sleep, and like to eat heavy flavored food such as sour and spicy food. Some people may experience loss of appetite, frequent urination, but not much urination each time, bilateral breast enlargement and sometimes swelling and pain, nipples and areolas darker than before, and small nodular protrusions on the areola. Early pregnancy reaction gradually disappears after 12 weeks of pregnancy and can be detected by testing the hormone level in urine or blood as early as 7 days after intercourse or 5-7 days after menstruation is delayed.