Urine protein 3 plus sign in late pregnancy is more serious and needs to be taken seriously. Urine protein with a plus sign found during pregnancy indicates that the kidney function is impaired to a certain extent, positive urine protein during pregnancy may have hypertensive disorders of pregnancy, kidney disease, systemic lupus erythematosus and so on. Urine protein with a plus sign during pregnancy is first considered to have hypertensive disorders of pregnancy, quantitative urine protein is an important indicator of diagnosis, so this time you need to timely diagnosis and treatment, active control of blood pressure, prolong the gestational weeks, as far as possible to ensure the safety of mother and child. Chronic nephritis and systemic lupus erythematosus can also have positive urine protein, which in severe cases can jeopardize the health of mother and child. There are no specific drugs for the treatment of chronic nephritis in pregnancy, which mainly lies in the protection of renal function, maintenance of water-electrolyte balance, and prevention of renal failure with serious complications. The use of SLE medication can affect the development of the fetus, which needs to be treated in conjunction with the condition as well as the doctor’s prescription. Urine protein positive need to see a doctor as soon as possible, active treatment.