Parkinson’s disease is a common degenerative disease of the central nervous system in the middle-aged and elderly, with an insidious onset and slow progression, mainly manifested by patients’ motor dysfunction, i.e., limb tremors, muscle rigidity, slow movement and abnormal posture and gait, which gradually worsens over time and eventually leads to patients’ inability to take care of themselves and reduces their quality of life. If the patient’s drug efficacy has gradually decreased, that is, when taking anti-Parkinson’s disease drugs in the peak concentration of drug efficacy is ideal, but the drug efficacy quickly fade or adverse reactions, such as switch phenomenon, end-of-dose phenomenon, isokinetic disorder, the disease has begun to affect normal work and life, at this time to receive deep brain electrical stimulation (DBS) treatment can obtain significant results. Zeng, a middle-aged and elderly male, developed stiffness and slow movement of the right upper limb 11 years ago with no obvious cause, and walked in a shuffling manner, and was diagnosed as “Parkinson’s disease” at the local hospital, and was given oral medroba, and the symptoms did not improve significantly after taking the medroba, and then stopped taking medroba, and then took oral medroba and senfuro again, and the symptoms improved significantly, and he reported that he was basically After the symptoms were further aggravated and the stiffness of the right lower limb and left limb appeared, and the movement was slowed, he went to a hospital in Shanghai and was diagnosed as “Parkinson’s disease”, and the symptoms improved significantly after the dosage was adjusted, but the duration of the drug effect was shorter than before. After taking the medication, the symptoms improved significantly, and the switch phenomenon appeared, and the duration of the drug effect was shortened. In order to seek further treatment, he came to our hospital for examination. Zeng was admitted to the hospital to improve relevant examinations and clarify the diagnosis. The patient was treated with local anesthesia + general anesthesia and underwent bilateral deep brain stimulation (DBS), and was given postoperative treatment to prevent infection, hemostasis, nerve nutrition and regular incisional dressing change. The patient’s general condition was acceptable, and he agreed to be discharged after consulting Dr. Wang, the chief physician. At the time of discharge, Zeng’s vital signs were stable, the incision was healing well, the stitches had been removed, and he was clear, mentally competent, and answering the questions. Zeng’s general condition was acceptable, no fever or signs of infection, and he was discharged. DBS is a deep brain electrical stimulation, commonly known as a pacemaker, which is performed through electrodes implanted in the brain to deliver electrical impulses to the relevant nuclei that control movement and regulate abnormal neural electrical activity, which can significantly improve the symptoms of bradykinesia/movement disorder, muscle rigidity and/or tremor in Parkinson’s patients, and can also significantly reduce the side effects of taking medications. Deep brain electrical stimulation for Parkinson’s disease is minimally invasive, safe, developable, reversible and adjustable. The procedure does not damage brain tissue and does not interfere with other new treatments in the future. It can adjust the stimulation parameters according to the patient’s specific situation, and also can achieve the best treatment effect by continuously adjusting the stimulation parameters as the patient’s condition changes.
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