There have been no clinical reports of side effects of Si Shen Wan, and there are generally no clear hazards associated with the use of this product under proper dosage and in accordance with medical advice. Si Shen Wan is a proprietary Chinese medicine. It is composed of nutmeg, bone marrow and jujube. It has the effect of warming the kidney, dispersing cold, astringing the intestines and stopping diarrhea. It is used for diarrhea caused by kidney yang deficiency (manifested as coldness, lumbago, coldness of limbs, decreased libido), symptoms can be seen as abdominal distension, loose stools (loose stools are not shaped), less food, prolonged diarrhea, cold limbs. Adverse reactions, contraindications, and precautions for Si Shen Wan are not known at this time. Chinese medicines or proprietary Chinese medicines need to be used under the guidance of a Chinese doctor to identify the evidence, and individuals should not use them blindly, so as not to use the wrong medicinal properties to cause adverse consequences.