Short-term staying up late may have little effect on uric acid, but long-term repeatedly staying up late will lead to an increase in uric acid. Because when staying up late, the body’s hormones will change accordingly, for example, normal people at 24:00 at night, cortisol is at its lowest state, when staying up late, the cerebral cortex will stimulate cortisol secretion, long-term increase in cortisol, promote human fat synthesis, metabolic obesity, cholesterol increases, the raw material for uric acid synthesis will increase. So long-term stay up late, hormonal disorders, which in turn lead to increased cholesterol, while increasing uric acid, it is still recommended to avoid long-term stay up late.