Definition: Osteoarthritis is a chronic joint disease characterized by degeneration and destruction of joint cartilage and osteophytes. Clinical manifestations: It is more frequent after middle age and mainly manifests as pain, swelling, morning stiffness, joint effusion and bony hypertrophy of the affected joints, which may be accompanied by bone rubbing sounds during activities, functional impairment or deformity. How to diagnose: It is mainly based on the patient’s clinical manifestations, physical signs and imaging and other auxiliary examinations. Treatment Treatment: Treatment is aimed at relieving pain, stopping and delaying the progression of the disease and preserving joint function. The treatment plan should be based on the condition of each patient. (1) General treatment (1) Physical therapy: including heat therapy, hydrotherapy, transcutaneous electrical nerve stimulation therapy, acupuncture, massage and tui-na, traction, etc., all help to reduce pain and relieve joint stiffness. (3) Reduce joint load and protect joint function: Excessive load should be avoided in the affected joints, and patients with knee or hip joint involvement should avoid prolonged standing, kneeling and squatting positions. Patients with knee or hip involvement should avoid prolonged standing, kneeling and squatting. Canes and walkers can be used to assist activities, and obese patients should reduce their weight. 2, drug treatment can be mainly divided into symptom control drugs, drugs to improve the condition and cartilage protection agents. (1) symptom control drugs: ① NSAIDs; ② other pain relievers, such as acetaminophen, tramadol, etc.; ③ local treatment, including local topical NSAIDs and intra-articular injection of glucocorticoids, hyaluronic acid preparations. (2) Improving the condition of drugs and chondroprotective agents These drugs have the effect of reducing the activity of matrix metalloproteinases, collagenases, etc., which can not only anti-inflammatory, pain relief, but also protect joint cartilage, and have the effect of delaying the development of osteoarthritis. The onset of action is generally slow. The main drugs include glucosamine, diacerein, etc. 3.Surgical treatment For patients with no obvious effect by medical treatment, serious lesions and obvious joint dysfunction can consider surgical treatment.