Swelling inside the urethra may be caused by frequent ejaculation, or it may be caused by diseases, such as glansitis and vaginitis. Frequent male masturbation will make the penis subject to long-term chronic friction, in addition to sex will lead to the urethral spongiosum continued congestion, long-term congestion will cause discomfort in the urethra. This will lead to the phenomenon of urethral swelling, stop the related stimulation, friction, masturbation, etc., then the urethral edema can gradually return to normal, generally no need for drug treatment. Male patients due to microbial infection and other factors lead to glans, inflammation stimulation will cause glans mucosa, urethra pain and swelling, can be accompanied by pain when urinating, itching and so on. Female vaginitis patients are often related to infection, dysbiosis and other factors, due to the proximity of the female vagina to the urethra, as the disease progresses may cause swelling of the urethra. When patients experience discomfort, they should go to the hospital immediately to clarify the cause of the disease and then be treated under the guidance of the doctor.