Most patients with chronic kidney disease are afraid of exercise, fearing that exercise will aggravate kidney disease, long-term, patients gradually feel a significant decline in physical strength, easy fatigue, muscle content significantly decreased, and muscle is one of the important components of the body, its important role is to carry oxygen for tissue and organs to feed, therefore, the decline in muscle content often means that the patient’s heart, lungs, cerebrovascular and other important organ function is reduced. It is really the rhythm of imminent death. In view of the above statement, it is very important and necessary for patients with chronic kidney disease to have moderate exercise and physical activity. The general recommendations are as follows: Firstly, change the sedentary lifestyle with little movement. Second: increase physical activity, starting with daily chores and daily activities, so that you can move first. Third: normal people should ensure at least 10,000 steps per day, and for patients with chronic kidney disease, you can gradually increase the amount of activity to 10,000 steps per day. Fourth: Chronic kidney disease is a special category of people, for such patients, we need to make a professional exercise prescription according to your physical condition, and to follow up closely.