Sometimes, the pain has already affected the quality of life, but they still try to maintain the poor quality of sleep, appetite and daily activities by “simmering”. Many patients, family members and even doctors may have doubts about whether cancer pain needs medication, under what circumstances it is necessary and how to use it. Cancer pain is a common symptom among patients with advanced cancer. Persistent and persistent pain will cause rapid deterioration of general condition, depression of immune function, and affect appetite and sleep to different degrees. If not eliminated in time, it is very unfavorable to cancer treatment. Many patients think that painkillers are addictive, and many of them even associate them with drugs such as dulcolax, and some non-oncology physicians do not know enough about cancer pain treatment and lack sufficient experience in using them. So how should cancer pain be correctly understood? With the construction of the National TCM Oncology Research Base of our hospital, we have accumulated certain experience in the treatment of advanced cancer pain in the previous clinical practice. The following is an overview of the treatment of cancer pain: The first thing that we emphasize in the standardized treatment of cancer pain is the assessment of cancer pain. In the outpatient clinic, we put great emphasis on the relationship between pain and patient’s sleep. Pain is divided into 0 to 10 points from mild to severe, with 0 representing no pain, 1 to 3 representing mild pain (sleep is not disturbed), 4 to 6 representing moderate pain (sleep is disturbed), and 7 to 10 representing severe pain (sleep is severely disturbed). The treatment of cancer pain is generally based on drug therapy, in addition to palliative radiotherapy, palliative chemotherapy, surgical treatment, nerve block therapy, nerve destruction therapy, nerve stimulation therapy and psychotherapy. Drug therapy and other treatment methods can be combined with each other. The basic principles of pharmacotherapy are as follows: Drug administration according to the patient’s pain is divided into three steps according to the degree of mild, moderate and severe pain. The first step of medication is non-opioid drugs represented by aspirin. Currently, anti-inflammatory pain suppositories are more commonly used in clinical practice. The second ladder is represented by codeine, a weak opioid. Chimantin is currently more commonly used. The third step of medication is morphine as the representative of the strong opioid drugs. Mescaline and OxyContin are more commonly used. The pain medications of different steps can be used in combination. In addition, corticosteroids, antidepressants, anticonvulsants, NMDA receptor antagonists, hypnotics and sedatives can be added to each step of the pain ladder to increase the analgesic effect. The use of analgesic drugs for cancer pain must be administered at regular intervals, such as every 6 hours or every 12 hours, rather than only when pain occurs, to ensure continuous pain relief. Oral (non-invasive) administration Whenever possible, oral (non-invasive) administration is preferred. Consider other routes of administration only if oral (noninvasive) methods are inappropriate or ineffective. There is no standard or maximum amount of opioid medication that can be administered individually. It should be stated that whatever provides pain relief without intolerable side effects is the correct dose. Patients on pain medication should be monitored and their reactions should be closely observed, with the goal of obtaining the best possible outcome with the least side effects. Effective preventive treatment can be given promptly for the more common side effects. Patients may still have pain when they do not find the right dose at the beginning of pain medication or pain medication replacement, so they should be patient and cooperate with the doctor to find the best dose for them. In conclusion, patients do not need to worry about drug addiction to endure cancer pain; through standardized treatment of cancer pain, most patients can achieve satisfactory pain relief, so that they can achieve “pain-free sleep, pain-free rest and pain-free activities” and their quality of life can be greatly improved.