Buttock groove long bumps are not necessarily the cause of AIDS. AIDS is called acquired immunodeficiency syndrome, mainly attacking the body’s immune system, due to the body’s immune system is a large number of destruction, impaired function, defective immune cell function will increase the chances of various infections, as well as the incidence of tumors, so it is the biggest cause of death of patients. In addition, pathological changes in the body caused by the early stages of AIDS may include enlarged lymph nodes, lymphoid follicular hyperplasia, as well as diseases of the blood system, which are manifested by changes in the medulla oblongata. There is also the possibility of lymphopenia in the spleen and thymus, which rarely causes in vitro changes. Certain sexual diseases, such as condyloma acuminatum may cause bumps to develop here, especially in men. Condyloma acuminatum occurs near the anus or on the glans, and in women around the anus. It is transmitted mainly through sexual contact and occurs throughout the entire range of intimate contact. In the early stages, small and pointed protrusions can appear, and in the late stages, larger nodules and cauliflower-shaped, it is recommended to go to the Department of Dermatology and Venereal Diseases in time for treatment.