Repeatedly high fever with rabies vaccine is usually caused by the adverse reaction of the vaccine, and the patient can take physical cooling and medication to lower the temperature. In addition, high fever caused by other factors such as upper respiratory tract infection can not be ruled out, if repeated high fever for more than 24 hours, you need to go to the hospital in time to avoid delaying the condition. Patients pay attention to diet and ensure sufficient rest after rabies vaccination. When patients have repeated high fever after rabies vaccination, it is an adverse reaction to the vaccine. High fever refers to a fever with a body temperature of more than 39℃. If the patient’s body temperature does not exceed 38.5 ℃, it is not recommended that the patient take medication to lower the temperature, the patient can use warm water or alcohol to wipe the body, but also to ensure that the indoor ventilation, appropriate increase or decrease in clothing, can help the patient to lower the temperature. If the patient’s temperature exceeds 38.5 ℃, you can take medication to reduce fever, patients can follow the doctor’s instructions to take ibuprofen extended-release capsules, acetaminophen tablets and other non-steroidal anti-inflammatory drugs. In addition, recurrent high fever does not exclude viral or bacterial infections and other causes, if the recurrent high fever lasts more than 24 hours, or there are convulsions, poor mental health, pallor and other symptoms suggesting an aggravation of the condition, it is recommended to go to the hospital in a timely manner, under the guidance of the doctor for further consultation and treatment, to make a definitive diagnosis, to avoid delaying the condition. It is recommended that patients who have received rabies vaccination adjust their diets in a timely manner, and patients should not eat too much spicy and stimulating food, such as onions, peppers, garlic, and so on. Patients should rest sufficiently, avoid staying up late or heavy physical labor. Patients with repeated high fever after rabies vaccination should take timely measures to lower the temperature, repeated high fever for more than 24 hours can go to the hospital for a clear diagnosis. The medication should be taken according to the doctor’s advice, not self medication.