The main hormones secreted by pancreatic islets are insulin and glucagon, which have the function of regulating blood glucose homeostasis, and once damaged, it will easily lead to abnormal glucose metabolism diseases such as diabetes mellitus. At present, there is no specific drug that can ensure the repair of pancreatic islet function, but the decline of pancreatic islet function can be slowed down by some suitable hypoglycemic drugs, such as Acarbose, Metformin, and so on. 1. Acarbose: It can be used with dietary control, mainly used to treat diabetes and reduce postprandial blood glucose in people with impaired glucose tolerance, common adverse effects include bowel sounds, diarrhea, abdominal distension, etc. It is prohibited for patients with severe renal impairment. 2. Metformin: It is suitable for patients with type 2 diabetes mellitus who are ineffective in the treatment of simple dietary control as well as physical exercise, and its main adverse reactions are nausea, vomiting, diarrhea, abdominal pain, abdominal distension, dyspepsia, fatigue, etc. It is forbidden to take it for patients with renal dysfunction caused by heart failure, acute myocardial infarction, as well as sepsis. During the period of taking the medicine, patients should pay attention to the observation of their own health status, do not self-medication, so as not to cause a variety of uncomfortable symptoms, such as nausea, vomiting and abdominal pain, etc., and go to the hospital on a regular basis for re-examination, to keep the blood glucose level within a reasonable range.