It is possible to brush your teeth for a new coronavirus nucleic acid. Brushing your teeth before the nucleic acid test has no effect on the results. Nucleic acid is collected from sputum and nasopharyngeal secretions in the deep part of the throat. Brushing before the nucleic acid test will not affect the collection of the specimen and will not affect the accuracy of the test results. Therefore, it is possible to brush your teeth before the nucleic acid test. It should be noted that it is best not to eat two hours before the nucleic acid test to avoid nausea, vomiting and other uncomfortable symptoms during the test. Do not do the nucleic acid test within 48 hours of receiving the new crown vaccine. When doing the nucleic acid test, be sure to keep a safe distance from others to avoid cross-infection.