Craniotomy is usually used for patients with craniocerebral injuries. Whether memory loss can be restored after craniotomy is related to the severity of the craniocerebral injuries suffered by the patients. For patients with less serious conditions, most of them can recover their memory gradually with the gradual stabilization and recovery of their conditions. If the craniocerebral injury is more serious, with massive cerebral hemorrhage, subarachnoid hemorrhage, etc., or if the patient has been in a coma for a longer period of time before the craniotomy, it is very difficult for the memory to recover, and it is possible that the memory will be lost forever. If craniotomy is needed, it is recommended to go to a regular hospital and choose a surgeon with strong professional ability to carry out the operation, so as to improve the success rate of the operation and avoid memory loss. At the same time, it is also necessary to strictly follow the doctor’s instructions for post-operative care, pay attention to rest, strengthen the dietary regimen, ensure that the dietary nutrients supplementation, and avoid eating too oily and spicy food, which will help the post-operative recovery.