Adrenal nodular thickening may be tumor or simple hyperplasia, which should be judged according to clinical manifestations and blood biochemistry and other relevant examinations. Adrenal nodular thickening may be caused by pheochromocytoma or other adenomas with endocrine function, which often leads to endocrine disorders, and a series of symptoms such as cardiac arrhythmia, hypertension and metabolic disorders may occur. It can be determined by clinical manifestations, blood tests, and CT of the adrenal glands. If the condition is simple hyperplasia, the patient may not have obvious symptoms and the hormone level does not change significantly, so there is no need for special treatment and regular review is sufficient. If the condition worsens in the later stage, progressive enlargement or tumor-like changes occur, or hormone levels become abnormal, it is necessary to consult a doctor in time for treatment. For patients with adrenal nodular hyperplasia, it is recommended to diagnose the condition under the guidance of a professional doctor, taking into account clinical symptoms, as well as blood tests, MRI and other tests.