When thyroid nodules are large, they may cause discomfort such as a foreign body sensation in the throat. The cause of thyroid nodules is still unclear, and most patients often have no conscious symptoms and may only find them unintentionally during checkups. As the disease progresses, the nodules increase in size, which may lead to discomfort such as a foreign body sensation in the throat, pain, coughing and shortness of breath. If the patient is combined with hyperthyroidism, he/she may also experience excessive sweating, palpitations, hand tremors, and weight loss; if combined with hypothyroidism, he/she may experience chills and generalized fatigue. Thyroid nodule patients who have a foreign body sensation in the throat or other uncomfortable symptoms should pay attention, go to the hospital as soon as possible, and follow the doctor’s instructions for treatment.