A high platelet pressure product in young children may be the result of diseases such as acute leukemia in remission, primary thrombocytopenic purpura; or acute blood loss or acute hemolysis; a slight elevation may also be due to physiologic factors. Platelet pressure product is the product of platelet count and mean platelet volume, while elevated platelet pressure product can be affected by platelet count and mean platelet volume. If a young child presents with acute leukemia in remission, primary thrombocytopenic purpura, myelodysplastic syndromes, megaloblastic anemia, and thrombophilia may result in a high mean platelet volume, and if the young child has an elevated mean platelet volume an elevated platelet pressure product will occur. In addition, acute blood loss, acute hemolysis, myelodysplastic syndromes, and chronic granulocytic leukemia in young children may result in high platelet counts, which may also result in high platelet pressure product. Some young children have only mild elevations, which may be transient due to physiologic factors, and are mostly individual variations that can be followed up with repeat examinations. It is recommended that parents of young children with high platelet count need to take their children to the hospital for examination in time, and the doctor will choose appropriate measures to treat the cause of the disease.