The period refers to menstruation, 44 years old menstruation 15 days is not clean, it is best to consult a doctor in time to check, may be irregular menstruation, uterine fibroids, endometriosis, but also may be related to cervical cancer and other diseases, need to be symptomatic line of medication or surgical treatment. 1. Irregular menstruation, 44-year-old women are in perimenopausal period, ovarian function gradually decline, may appear irregular menstruation symptoms, generally normal, can take oral antiemetic drugs, progesterone drugs treatment, such as Yunnan Baiyao capsule, dydrogesterone and so on. If necessary, perform curettage. 2. Uterine fibroids, if you have uterine fibroids, the gradual increase of fibroids may cause the endometrium to increase in scope, so there may be symptoms of dribbling menstruation, generally can be treated with surgery to remove the fibroids, to avoid increased bleeding. 3. Endometrial lesions, for patients suffering from endometrial polyps or endometrial cancer, the phenomenon of 15 days of irregular menstruation may also occur, and it is generally recommended to perform hysteroscopic endometrial polypectomy or endometrial cancer staging surgery. 4. Cervical cancer, if there is cervical cancer, the cancer cells invade the normal tissues, which may cause the bleeding to last for a long period of time, and it is necessary to actively consult doctor for surgical treatment to remove the diseased tissues, so as to avoid the danger of life. Regular medical checkups are needed in normal times, and more attention should be paid to personal hygiene to keep clean.