The four plus polio or five vaccines prevent the same diseases and have basically the same effect. Pentavalent vaccine has the advantage of reducing the number of vaccinations, but the cost is higher; quadruple plus polio vaccination is more frequent, but the cost is lower, so the two options have their own advantages, you can choose according to your own situation. The full name of quadruple vaccine is cell-free combined Haemophilus influenzae type b vaccine, and the full name of pentavalent vaccine is adsorbed cell-free combined inactivated polio and Haemophilus influenzae type b vaccine. Quadruple vaccine is less preventive against poliovirus than pentavalent vaccine, so quadruple plus polio vaccine and pentavalent vaccine are the same for preventing diseases. Both are safe and effective. Compared with the Pentavalent vaccine, it can reduce the number of times of vaccination a few times, and at the same time reduce the cost of vaccination time and the risk of vaccination complications, but the cost is higher, and the quadruple plus polio vaccination will be more often, but the cost is lower, so you can choose it according to your own situation. There are advantages and disadvantages to both the quadruple plus polio and pentavalent vaccine programs, so you can evaluate and choose according to your own situation, but the more important thing is to vaccinate your baby on time to effectively prevent diseases.