Hepatitis B core antibody positive and other negative indicates that the patient has been previously infected with the hepatitis B virus or that the patient is in the window period of infection. Hepatitis B core antibody is positive and others are negative, probably because the patient has been infected with Hepatitis B virus in the past and has been cured, so Hepatitis B surface antigen, Hepatitis B e antigen, etc. are negative, and since Hepatitis B surface antibody, a protective antibody, is also negative, the patient can be injected with the Hepatitis B vaccine to enhance the protective power. If the patient is infected with hepatitis B virus and is in the window period of 2 weeks to 3 months after infection, then there will also be the performance of hepatitis B core antibody positive and other negative. After the window period has passed, the examination of hepatitis B two halves can be carried out again, and it can often be found that the hepatitis B surface antigen, hepatitis B e antigen, and hepatitis B e antibody have turned to be positive. If the test finds that hepatitis B core antibody is positive and others are negative, it is recommended to consult a physician for further diagnosis and treatment under the physician’s guidance.