1, choose wide fit clothes, especially underwear can not be too tight, as far as possible to choose the material of pure cotton products. 2, hypopigmentation is generally a chronic process, to maintain a relaxed mood, keep serving a cheerful and open-minded, avoid agitation, worry, thinking, sadness, anger and other adverse emotional stimuli. 3, the establishment of a good routine, pay attention to the combination of work and rest, avoid staying up late, fatigue and too much work pressure, so as to avoid disruption of the body’s biological clock, neuroendocrine disorders. 4, diet rich in tyrosine and mineral foods and crustaceans, such as pork, chicken, black sesame, eggs, black fungus, black beans, peanuts and so on. Eat less food with high vitamin C content, such as tomatoes, apples, oranges and so on. 5, stable period of appropriate out of the sun, the acute development period to avoid excessive sun exposure. 6.Reduce or avoid contact with rubber gloves: because rubber protective gloves contain hydroquinone monophenyl ether, which is an antioxidant, and hydroquinone monophenyl ether has a selective destructive effect on melanocytes in the skin.