During the natural menstrual cycle, FSH and LH released by the pituitary gland stimulate the development of a number of follicles each month, and eventually only one dominant follicle develops and ovulates. In order to improve the economic efficiency of “test tube”, try to let the patient get the right amount of good quality eggs in one cycle of ovulation, so as to increase the clinical pregnancy rate, the use of controlled super-ovulation, as the name suggests, that is, within a controlled range, the use of exogenous gonadotropins, increase the collection of follicles per cycle, to relieve the body of the “setting” of the development and maturation of only one dominant follicle per cycle, so that only one dominant follicle will develop and ovulate. This allows multiple follicles to develop and mature at the same time. Most IVF patients are able to obtain multiple mature eggs in a single cycle, which are successfully fertilized and result in good quality embryos for transfer or freezing. A small percentage of patients, however, often fail to obtain eggs or obtain a very small number of eggs of poor quality in a single cycle of ovulation, which cannot be fertilized or do not fertilize properly to form an embryo. What are the reasons? It is easy to realize that such patients are in the minority and most of them are elderly patients or patients with premature ovarian failure. If you have read the previous articles, you must have realized that the fertility of a woman plummets after the age of 35, and the number and quality of eggs available in the ovaries are significantly reduced. “A poorly functioning ovary makes it difficult to obtain a satisfactory number of eggs, even with the best medication and increased dosage. Moreover, aging is an irresistible force of nature, and “dead” eggs cannot be regained. So, should such patients give up? Not necessarily, some patients, ovarian function is not to the degree of complete hopelessness, experienced doctors, may explore other methods of ovulation promotion, each person’s sensitivity to different drugs are different, it is possible that a change in a way to promote ovulation, you can get the optimal outcome. In addition, your mood and physical condition will also affect the outcome of ovulation induction to a certain extent. Therefore, if you have failed ovulation induction, adjust your mood, cooperate with your supervising physician, and follow the instructions for the next treatment plan.