People with prostatitis have a higher risk of prostate cancer than normal people. Prostate cancer (PCa) is the most common malignant tumor of the male reproductive system. Its etiology has not been identified and may be related to genetics, environment, and sex hormones. The secretory function of the prostate is regulated by the androgen testosterone, and the luteinizing hormone of gonadotropins plays an indirect role. Prostatitis refers to acute and chronic inflammation of the prostate gland caused by specific and non-specific infections, resulting in systemic or localized symptoms. Prolonged and repeated inflammatory stimulation of the prostate can prompt conversion to prostate cancer. National studies illustrate that histologic chronic prostatitis has a significant effect on PSA, Gleason score, and metastasis rate of prostate cancer, promoting the development of prostate cancer. If prostatitis is suspected or diagnosed, it is recommended to go to a regular hospital for comprehensive assessment of the condition and follow the doctor’s instructions to cooperate with the treatment, so as not to delay the condition.