Seborrheic keratosis of the skin can be treated using cryotherapy, laser therapy, and surgery. 1. Cryotherapy: Cryotherapy with liquid nitrogen may require multiple treatments. Hyperpigmentation or depigmentation spots may appear locally after treatment. 2. Laser treatment: At present, Q-switch, intense pulsed light, super pulsed CO2 laser and other laser treatments can be used, which may require multiple treatments depending on the situation. 3. Surgery: Surgical excision and histopathologic examination are available. Patients with seborrheic keratosis generally do not need treatment, but if for aesthetic reasons, it is recommended to go to the hospital and choose the appropriate method of treatment under the guidance of the doctor.