The symptoms can be relieved after proper adjustment of emotions and habits. If the patient’s symptoms are too serious, it may be caused by disease factors, such as mental illness, cardiovascular disease, endocrine disease, it is recommended that timely medical treatment. 1, mental illness: such as depression, anxiety disorders and other diseases of patients, due to emotional abnormalities, may appear all the time no energy and no energy situation. Patients are not accompanied by excessive organic lesions, but will appear anxiety, depression and other abnormal emotions; 2, cardiovascular diseases: such as hypertension, myocardial infarction, cerebral infarction, vascular sclerosis, etc., because of the weakening of blood circulation leads to reduced blood supply to the brain, brain hypoxia and thus the symptoms of being drained of energy and spirit. Patients often have blood pressure or lipid abnormalities, palpitations, panic, insomnia, dizziness, headache, and even unfavorable speech symptoms; 3, endocrine diseases: such as hypoglycemia, hypothyroidism, hypoadrenocorticism and other endocrine diseases, due to abnormal hormone levels in the body, may lead to the patient’s symptoms of being drained. It is recommended that patients should be examined, and there are mostly abnormalities in hormone levels, and some patients will also experience changes in food intake and weight; 4. Other diseases: such as lung cancer, liver cancer and other wasting diseases, the body consumes nutrients too fast and cannot supply energy, thus showing symptoms of being drained and lacking energy all the time. Patients are mostly accompanied by obvious symptoms such as reduced resistance and wasting. In addition, there are many clinical causes that may cause the symptom of being drained and weak, such as anemia, electrolyte disorders, sleep apnea syndrome, hypoproteinemia, tuberculosis, etc. Therefore, it is recommended that patients should seek medical treatment as soon as possible when more serious symptoms occur.