Foot fungus, the scientific name is also known as tinea pedis. The blisters (i.e. blisters) are getting more and more after using the medication, which may be related to factors such as medication not being appropriate, irregularity in the use of medication and adverse reactions to the medication. 1. Drugs are not symptomatic: tinea pedis is a skin disease caused by fungal infection, need to choose a broad-spectrum and efficient antifungal drug treatment, such as topical miconazole nitrate cream, naftifine ketoconazole cream, if necessary, follow the doctor’s instructions oral itraconazole capsules. If the medication is not appropriate, it will affect the recovery of the disease, so that the disease continues to progress, resulting in aggravation of the condition of blisters. 2. medication is not standardized: whether it is external drugs or oral drug therapy, need to achieve a certain concentration of drugs to have an antifungal effect, if the number of external drugs used incorrectly, the treatment time is too short, etc., or oral drugs intermittent use, the dose is too small, etc., will affect the therapeutic effect of the drug, so that the condition is getting more and more serious, the appearance of more and more blisters after the use of the drug phenomenon. 3. Adverse drug reactions: some antifungal drugs in the treatment process may appear itching, burning, blisters and other adverse reactions, such as miconazole nitrate cream. When the adverse reaction is serious, you must stop using it in time, clean it up and consult a doctor in time. It is recommended that patients with athlete’s foot have more and more blisters after using the drug, need to ask the doctor to interview and analyze the actual situation, and follow the doctor’s instructions to standardize the treatment.