Crohn’s disease is a chronic inflammatory disease that can occur in the oral cavity, esophagus, stomach, small intestine, cecum, and anus, but is generally more prevalent in the terminal part of the small intestine, such as the terminal ileum. The possibility of self-remission exists in some patients with mild symptoms, but there are no specific drugs available, so this disease has a high recurrence rate and is more difficult to cure. However, with aggressive clinical intervention, symptoms can be effectively relieved and complications can be reduced. Clinical symptoms of Crohn’s disease include prolonged abdominal pain, usually worse after eating and relieved by defecation or anal venting; and diarrhea, with predominantly pasty stools. The disease is a long-term wasting disease, so it can also cause weight loss. Clinical treatment of Crohn’s disease is mainly focused on controlling inflammation, and the inflammatory response can be controlled by aminosalicylates, glucocorticoid drugs, immunosuppressants, antibacterial drugs, and biological agents under the guidance of a physician, and symptomatic treatment is actively given. In addition, if complications such as intestinal obstruction, intestinal fistula, or acute intestinal perforation occur, timely surgery should be performed to remove the mechanical cause. If you have Crohn’s disease, you should follow your doctor’s instructions and take your medication, increase physical exercise, quit smoking and drinking, and take a balanced diet with vitamins and minerals to enhance your health. Crohn’s disease generally runs in families, and people with a family history of Crohn’s disease are advised to visit the hospital regularly for endoscopic screening so that the disease can be detected and treated at an early stage.