Disulfiram-like reaction, also known as withdrawal sulfur-like reaction, is a toxic reaction caused by the accumulation of acetaldehyde in the body caused by drinking alcoholic beverages or exposure to alcohol after the application of drugs, which can manifest as facial flushing, blurred vision, dizziness, nausea, chest pain and difficulty in breathing. The following drugs can cause this reaction: 1. antibacterial drugs: 1. cephalosporins: cefoperazone, cefamandole, cefotaxime, ceftriaxone, cefazoxime, cefazolin, cefixime, cefaclor, etc.; 2. imidazole antibacterial drugs: metronidazole, tinidazole and ornidazole, etc.; 3. other drugs: furazolidone, furantoin, chloramphenicol, ketoconazole, ashwagandha, erythromycin etc. Hypoglycemic drugs: common ones are chlorpropamide, toluenosulfonylurea, phenelzine, glibenclamide, gliclazide, glipizide, tolarsulfonylurea and insulin, etc. Third, other drugs: such as warfarin, trifluoperazine, chloral hydrate and cyproterone acetate. Alcohol should be avoided during treatment with the above drugs, and alcohol-containing drug preparations such as deciduous water, patchouli oral solution, medicinal wine preparations, tinctures and spiritus, etc. Alcohol-containing topical disinfectant skin preparations and topical rubbing alcohol for cooling should also be avoided.