After eating cephalosporins can generally drink alcohol after 7 days, depending on the specific drug, the time may be slightly extended to 10 days. Cephalosporin metabolism in the body is generally known as half-life, different drugs have different half-life, general cephalosporins need to be metabolized after 7 days, some drugs such as ceftriaxone sodium half-life is longer, need to extend the time appropriately, it is recommended to drink alcohol after 10 days, to avoid the occurrence of disulfiram reaction. Drug metabolism is generally in the liver and kidneys, depending on the state of the patient’s liver and kidney function, when the liver and kidney function is poor or severe damage, the metabolism time is prolonged, and the concentration of the drug in the blood is high, and you want to drink alcohol needs to be appropriately prolonged. Cephalosporins can produce disulfiram-like reaction with alcohol, resulting in patients with palpitations (rapid heartbeat, often accompanied by panic), headache, flushing and other typical symptoms, so follow the doctor’s instructions to use the drug, and try to drink alcohol after the drug is completely metabolized.