Vitamin B1 and vitamin B12 are both water-soluble B vitamins. Vitamin B1 is mainly used for the prevention and treatment of diseases caused by vitamin B1 deficiency, such as beriberi, neuritis, indigestion, etc., while vitamin B12 is mainly used for megaloblastic anemia, It can be used to treat neuropathies such as facial neuritis, polyneuritis, peripheral neuritis, sciatica, neuralgia left over from herpes zoster, and neuropathy caused by cerebrovascular disease in the posterior period and diabetes. The common dose of vitamin B1 is usually 100mg intramuscularly, and vitamin B12 is usually 500μg intramuscularly, either once a day or once every other day.