Feeling soreness and tenderness twenty days after minimally invasive surgery for synovial inlay in knee joint may be caused by muscle atrophy, calcium deficiency, or osteochondritis dissecans of knee joint. Depending on the cause, rehabilitation exercises, calcium supplements, oral ibuprofen and acetaminophen can be taken to relieve the symptoms. 1. Muscle atrophy: after minimally invasive surgery for synovial impaction of the knee joint, as patients do not carry out rehabilitation exercises in time, the reduced mobility leads to muscle atrophy, and the symptom of leg soreness and weakness will appear. It is recommended to carry out appropriate leg muscle exercise to prevent muscle atrophy. 2. Calcium deficiency: the symptoms of leg weakness can also occur when the patient lacks calcium. It is recommended to supplement calcium tablets or liquid calcium, which can effectively relieve the symptoms. 3. Osteochondritis Dissecans of the knee joint: poor care of the knee joint synovial embedded minimally invasive surgery has led to the emergence of osteochondritis dissecans. If there is liver pain in the affected Antibiotics can be used for treatment, and patients with severe symptoms can take ibuprofen and acetaminophen orally to relieve symptoms. It is recommended that patients who feel tenderness twenty days after minimally invasive surgery for synovial implantation in the knee should go to the hospital promptly to clarify the cause of the problem. If you need to use drugs, it is recommended to use under the guidance of a doctor.