High aminotransferase may suggest viral hepatitis, alcoholic liver disease, drug hepatitis, etc. According to the cause, antiviral drugs, liver-protecting and enzyme-lowering drugs, prohibition of alcohol, stopping liver-damaging drugs, etc. should be given to nourish the liver. 1. Viral hepatitis: such as hepatitis B virus infection can be given entecavir, lamivudine and other antiviral treatment; hepatitis C virus infection can be given sofosbuvir, velpatasvir and other drugs. 2. Alcoholic liver disease: strictly prohibit alcohol, give polyene phosphatidylcholine, compound glycyrrhizin and other hepatoprotective drugs. 3. Drug-induced hepatitis: it is necessary to stop taking liver-damaging drugs, and to combine acetylcysteine, glutathione and other drugs for treatment. The above drugs should be used under the guidance of professional physicians. It is recommended to consult a doctor in time for elevated aminotransferases, and follow the doctor’s instructions to take medication, do not take medication on your own.