The cause and pathogenesis of thyroid nodules are still unknown, and many people have thyroid nodules that may be caused by genetics, irregular diet, radiation, stressful life, and low body immunity. Thyroid nodules are genetically related, and hereditary enzyme defects may lead to impaired hormone synthesis, increasing the probability of developing thyroid nodules. Too much or too little iodine intake in people’s lives may lead to thyroid nodules. Prolonged exposure to bad moods may affect the normal synthesis of hormones in the body and may also increase the probability of developing thyroid nodules. In addition, a lowered immune system is susceptible to disease, which may lead to the development of thyroid nodules. Patients with thyroid nodules are recommended to be seen by a doctor.