There is no contraindication between Si Miao Pill and Liu Wei Di Huang Wan, but the drug should be used under the guidance of a doctor. Si Miao Pill is composed of Cangzhu, Ox Knee, Huangbai and Coix Seed, which has the effect of clearing heat and inducing diuresis, and can be used to treat paralysis due to dampness-heat. Pregnant women need to use this medicine with caution. Liu Wei Di Huang Pill is composed of Radix Rehmanniae Praeparata, Rhizoma Dioscoreae, Rhizoma Dioscoreae, Cornu Cervi Pantotrichum, and Rhizoma Zedoariae, which is effective in nourishing yin and tonifying kidney. It can be used to treat soreness and weakness of the waist and knees, hot flashes, and night sweating (abnormal sweating after going to sleep, but sweating stops after waking up) caused by insufficient kidney yin. Patients with cold and fever should not use this medicine. There is no contraindication between the above two drugs, so they can be used at the same time. However, the drugs have their own indications. Patients with dampness-heat underflow (dampness and heat evils invading the intestines, bladder, pubic region, lower limbs, etc.) and insufficient kidney yin are more suitable for concurrent use of the drugs. Patients who need to use the drugs should consult a Chinese medicine practitioner and should not use them on their own.