Colds generally refer to upper respiratory tract infections, and antigen testing for patients with upper respiratory tract infections generally has no effect. Because antigen tests are designed to detect specific pathogens, such as the new coronavirus, the results of antigen tests will not be negatively affected even if the patient is infected with a pathogen after a cold. However, it is generally not recommended that patients smoke or drink alcohol prior to the antigen test to prevent the accuracy of the test results from being affected. If the antigen test result is positive, the patient is infected with the virus and needs to be quarantined in a hospital as soon as possible to prevent spreading the infection to others. If the test result is negative, the possibility of infection with the new coronavirus cannot be completely ruled out, especially for people with a history of close contact, and follow-up testing is still needed. Patients with upper respiratory tract infections are usually not affected by antigenic testing and are advised to go to their local hospitals for antigenic testing to determine whether they are infected with the corresponding pathogens.