Bone marrow edema in children is not an early symptom of leukemia. Bone marrow edema is mostly caused by trauma and local congestion. Early symptoms of leukemia mainly include fever and anemia. 1. Fever: mostly different degrees of fever and fever type. Fever is mainly caused by infectious factors, and sepsis and septicemia may occur in patients with serious condition. Fever can be a manifestation of acute leukemia itself. 2. Bleeding: bleeding symptoms should not be ignored, the patient’s whole body will produce bleeding symptoms, bleeding symptoms are mainly manifested as skin and mucous membrane bleeding, including nosebleeds, gum bleeding, oral blisters, skin bleeding spots and so on. 3. Anemia: early onset children with anemia symptoms are particularly obvious, including pale, dizziness, fatigue, headache, decreased activity endurance, dyspnea after activity and other adverse symptoms. Children in the developmental stage should guard against the emergence of leukemia, parents and friends will be the early symptoms of the disease to understand thoroughly, once diagnosed with leukemia, you should take the child to the hospital as soon as possible for treatment.