Neonatal jaundice for 4 days is 15~16mg/dl, it depends on whether the baby has high-risk factors, if there are high-risk factors, then it has exceeded the corresponding age and the relevant risk factors phototherapeutic intervention standards, belongs to the pathologic jaundice, and should be treated in a timely manner. If it is low risk, it can be left untreated for the time being. Normal newborn serum total bilirubin is 5~7mg/dl, over which jaundice is visible to the naked eye. High risk factors for a jaundiced baby include: homozygous immune hemolysis, glucose-6-phosphate dehydrogenase deficiency, asphyxia, significant lethargy, temperature instability, sepsis, metabolic acidosis, and hypoalbuminemia. Distinguish whether a baby is high risk (preterm + risk factors), intermediate risk (term + risk factors) or low risk (term and no risk factors) based on risk factors. 1. Newborns with 4-day jaundice of 15-16mg/dl can be left untreated if they do not have any of the above high-risk factors. 2. If the neonate has the above risk factors and the 4-day jaundice of 15~16mg/dl exceeds the standard of phototherapy intervention for the corresponding day age and related risk factors, it is pathologic jaundice and should be treated in time to avoid bilirubin encephalopathy, which affects the neurological development of young children. Common pathological jaundice treatments include phototherapy, drug therapy, blood exchange therapy or other treatments, which should be promptly consulted and treated under the guidance of a doctor.