Redness and peeling on the sides of the nose can be caused by physiologic factors, such as dry skin. It can also be caused by pathologic factors such as rosacea or seborrheic dermatitis. It is recommended to improve the condition through physical therapy and medication after clarifying the specific cause under the guidance of a doctor. 1. Dry skin: For patients with dry facial skin, there may be redness and peeling on both sides of the nose. At this time, patients can use topical moisturizing products such as urea ointment, and if necessary, can be improved through medical means, such as injections of hydrafacial needles. 2. Rosacea: Rosacea may be associated with heredity, sun exposure, and skin barrier damage. Patients can use topical medications to promote skin barrier repair, such as recombinant bovine basic fibroblast growth factor gel to improve the redness and peeling of the nose. 3. Seborrheic dermatitis: Seborrheic dermatitis may be related to heredity and Malassezia infection. Patients can take oral vitamin B6 under the guidance of the doctor to regulate the secretion of oil, and can also use topical calcium-modulated phosphatase inhibitors such as tacrolimus ointment and pimecrolimus ointment for anti-inflammatory treatment. When the patient’s nose on both sides of the phenomenon of redness and peeling, it is recommended to go to the regular hospital for examination in a timely manner, under the guidance of a professional doctor for standardized treatment. Drugs need to be used in accordance with medical advice.