Clinically, dry and cracked lips and blisters are more common, patients can be treated symptomatically according to different causes, generally including the following cases: 1, fire, caused by eating more spicy food, drinking too little water, etc., causing fire will appear this symptom, patients can drink more water, usually can take multivitamins, try to reduce the intake of spicy, stimulating food, but also oral cefixime, roxithromycin and other drugs The patient can be treated with mupirocin ointment or neomycin ointment, as well as with ribavirin and interferon for systemic antiviral treatment, which can effectively improve the symptoms, and the local blisters should not be picked by themselves to avoid infection and wait for them to heal on their own. The localized blisters should not be picked by themselves to avoid infection, and they should wait for their healing.