Postoperative pathology report of breast cancer is one of the important bases for follow-up treatment. Patients and family members are often confused by the contents of the report card and do not know what it means. Histological types of invasive carcinoma include invasive ductal carcinoma and invasive lobular carcinoma, etc. The prognosis is relatively poor and requires subsequent radiotherapy and chemotherapy. 2.Depends on the histological grading: Generally, it is graded from I to III. The higher the grading, the higher the malignant degree. 3.Look at the location and size of the tumor: for every 1cm increase in the maximum diameter of the tumor, the risk of recurrence and metastasis increases by 12%. If the tumor is greater than or equal to 5cm, it is an indication for postoperative radiotherapy. 4.See the surgical margin: see if the surgical margin is positive, if it is positive, it needs to be operated again or radiotherapy as soon as possible. 5.See if the cancer is found in the artery or vein in the local area, which indicates that there is a higher possibility of bloodstream metastasis and a relatively poor prognosis. 6.See whether the tumor invades the breast skin and chest wall: if it does, postoperative radiotherapy is recommended. 7. Look at the metastasis of axillary lymph nodes: axillary lymph node metastasis is an important prognostic indicator, which is expressed by XMY. X represents the number of metastatic lymph nodes, Y represents the number of pathology sent for examination. For example, 2/12 means 12 lymph nodes were examined during surgery and 2 of them had cancer metastasis, the greater the X value, the worse the prognosis. In the past, experts believed that radiotherapy is recommended after radical surgery for breast cancer with 4 or more lymph nodes metastasis, but now it is found that breast cancer with 1-3 lymph nodes metastasis benefit from radiotherapy to varying degrees, therefore, more doctors will recommend radiotherapy now. 8. Look at the hormone receptor test: ER: estrogen receptor, PR: progesterone receptor, reflecting whether the tumor is regulated by hormones. If ER (+) and/or PR (+), it means that endocrine therapy can be done after surgery, and the literature reports that endocrine therapy can reduce the risk of recurrence by 50% in patients with ER (+) and/or PR (+). 9. Look at immunohistochemistry single C-erbB-2 /HER-2: C-erbB-2 (C), (+) is judged as negative, C-erbB-2 (+++) is judged as HER-2 positive, C-erbB-2 (++) needs to be further clarified by Fish test if there is amplification of Her-2 gene to decide whether to use Herceptin treatment. 10. ki-67 test: generally expressed as a percentage, it is the most important indicator of cell proliferation, the higher the positive rate, the worse the prognosis. 1. Radiotherapy after breast-conserving surgery for early-stage breast cancer 1.1 Indications Radiotherapy is required after breast-conserving surgery for early-stage breast cancer. 1.2 Start time of radiotherapy The first radiotherapy after breast-conserving surgery should be started within 4-6 weeks after the incision healing. 1.3 Radiotherapy technique and dose Three-dimensional conformal or intensity modulation techniques can be used. The whole breast irradiation dose is 45-50 Gy, 1.8-2Gy/time, 5 times/week. After whole-breast irradiation, a supplementary dose of 10～16Gy/5～8 times is usually required in the tumor bed area. 2.Radiotherapy after radical surgery or modified radical surgery for breast cancer 2.1 Indications Post-operative radiotherapy is required for one of the following high-risk factors: a. The maximum diameter of the primary tumor is ≥5 cm, or the tumor invades the breast skin or chest wall; b. Axillary lymph node metastasis is ≥4. c. T1/T2 patients with one to three axillary lymph node metastases, especially with the following high-risk recurrence risks: age ≤ 40 years, number of axillary lymph node dissection < 10, proportion of axillary lymph node metastases > 20%, hormone receptor negative, Her-2/neu overexpression, radiotherapy can also be considered. 2.2 Postoperative radiotherapy site and dose The chest wall and supraclavicular are the conventional target areas for postoperative adjuvant radiotherapy. The conventional dose of postoperative adjuvant radiotherapy is 50 Gy/5 weeks/25 times, and the dose can be locally increased to 60 Gy or more for areas with high suspicion of residual.