Generally, eczema of the pubic area occurs in the scrotum, while penile eczema is less common. The main symptoms are erythema, papules, scaling, vesicles, oozing, crusting, scratching and other skin manifestations, and accompanied by a certain amount of itching or stinging pain. Because the penile area is sensitive, you should be very careful in the use of medication. In the choice of oral medication, you can choose antihistamines, such as chlorpheniramine maleate tablets, loratadine tablets, levocetirizine hydrochloride tablets, olopatadine hydrochloride tablets or epinastine hydrochloride tablets, and you can also take oral compound glycopyrrolate capsules. In severe cases, the patient can be treated with a combination of glycyrrhizin injection and topical application of 2% boric acid solution.