The main advantage of nuclear medicine bone imaging is its high sensitivity in the detection of bone disease and its ability to show the presence of lesions much earlier than the appearance of abnormalities on X-ray. In most cases, bone imaging can detect bone metastases at an early stage, usually 3-6 months or even earlier than X-ray bone films; because a single imaging can understand the whole body skeleton, it can detect lesions beyond the scope of X-ray examination, and in addition, in some hidden or subtle fractures such as crack fractures of the ribs and fractures of the navicular bone of the wrist, which cannot be detected initially by X-ray, but only at follow-up review. In addition, in some hidden or subtle fractures such as cracked rib fractures and fractures of the navicular bone of the wrist, which cannot be detected by initial X-ray but only during follow-up review, bone imaging can make timely diagnosis. The main shortcoming is that the specificity is not high, that is, almost all bone diseases will show abnormal distribution of radioactivity on bone imaging, so it is difficult to make a definite diagnosis of bone disease based only on isolated localized areas of increased (or decreased) radioactivity on bone imaging.