Can not sleep during the day and night, consider the existence of sleep disorders, the reasons are as follows: 1, due to overwork, mental tension, or stress leading to sleep disorders, can also be seen in patients due to environmental changes, resulting in day and night can not sleep, there is also a disruption of the work and rest time, affecting the biological clock, can also appear day and night can not sleep. 2, day and night can not sleep, can also be seen in organic diseases The most common is gastrointestinal diseases, due to acid reflux, belching and other symptoms after eating, which can affect the patient’s sleep. Coronary artery disease, myocardial ischemia, or angina pectoris, arrhythmia, etc., due to abnormal heart ejection, can affect patients with symptoms such as chest tightness, panic, etc., can also affect the patient’s sleep appearing day and night sleeplessness. 3, clinically most often seen in patients with anxiety and depression, due to emotional abnormalities leading to sleep disorders, can be given to improve anxiety, depression oral medication. 4, organic brain Diseases, such as autoimmune encephalitis, some patients part of the symptoms manifested as insomnia, accompanied by other neurological symptoms and psychiatric symptoms, etc.