Cystic nodules grade II in both breasts is a common disease in women’s breast, most of them are benign lesions, further mammograms can be done to clarify the diagnosis, and regular review is usually needed to deal with the problem in time. Cystic nodules are cystic hyperplastic lesions of the breast, which may cause slight swelling and pain around the time of menstruation, and some patients have no special discomfort and are found by chance during health checkups or bathing. If the nodule is relatively small and the ultrasound indicates no blood flow signal, regular ultrasound follow-up can be done for observation. If the cystic nodule gradually increases in size, with strong blood flow signal and periodic pain with menstrual cycle, early surgical excision and histological biopsy is recommended to clarify the diagnosis. Cystic nodules in the breast are related to female endocrine, emotion or personality.