The amputation rate of diabetic patients is higher than that of non-diabetic patients, commonly due to poor blood sugar control for a long time, combined with lower extremity atherosclerosis occlusion, and also combined with diabetic peripheral neuropathy, the patient has numbness in both lower extremities, insensitive to pain and temperature sensation, and often has burns and abrasions. If the patient’s blood sugar is significantly elevated, he or she is prone to develop diabetic foot and infection. If patients with diabetic foot co-infection cannot be treated early with anti-infection treatment, as well as nerve nutrition, circulation improvement and surgical debridement, the patient’s condition will often progressively worsen, and the course of the disease will progress rapidly, often resulting in local foot necrosis, infection, poisoning and other symptoms, easily leading to amputation, and the risk of infectious shock. Therefore, diabetic patients should undergo early standardized glucose-lowering treatment, so that blood glucose, blood pressure and lipid control can reach the standard and reduce the occurrence of chronic complications in diabetic patients, thus reducing the rate of amputation in diabetic patients.