The seriousness of multiple nodules in the bilateral lobes of the thyroid gland is objectively analyzed based on factors such as the volume, size, and different nature of the thyroid nodules: i. If the thyroid nodules are large in size, accompanied by local symptoms of tracheal, esophageal, and nerve compression, patients show clinical manifestations such as hoarseness, choking on water, and difficulty in breathing. Ultrasound examination reveals nodules with obvious calcification, rich blood flow, and malignant signs such as aspect ratio greater than 1. In this case, the nodules are considered to be cancerous. If the nodules are not surgically removed in time, they may cause extensive metastasis of cancer cells and serious complications. Second, if the nodules in bilateral lobes of thyroid gland are small in size, ultrasound examination indicates that the nodules have clear borders, regular shape and uniform echogenicity. In this case, the nodules are considered to be benign lesions, and there are no obvious symptoms of pressure on the nodules, which will not cause serious impact on the human body, so close observation is recommended and surgery is not needed for the time being.