Generally speaking, hepatitis B minor triple positive mainly refers to hepatitis B surface antigen positive, hepatitis B core antibody positive and hepatitis B e antibody positive in hepatitis B triple system. The three positive should be considered that the patient’s virus is not replicating and the virus replication is in the resting period, at this time, if the patient’s liver function is normal, there is no need to take medication, and only need to observe regularly, check the three systems of hepatitis B, liver function and hepatitis B DNA every half a day, and if there is still no viral replication and in the status of small triple positive, the patient can continue to observe. If the patient has virus replication, it suggests that hepatitis B surface antigen is positive, hepatitis B e antigen is positive and hepatitis B core antibody is positive. The patient needs to take further antiviral medication and active antiviral treatment, or inject interferon and active antiviral treatment for about half a year. If there are also elevated ghrelin and ghrelin aminotransferase, patients need to take hepatoprotective drugs to continue active treatment.